The History, Science, And Art Of Wine And The Case For Health Benefits: Perspecitives Of An Oenophilic Cardiovascular Pathologist

This article stems from the intersection of the author’s long-standing interests in science, medicine, pathology and oenology. A discussion is provided of selected aspects of the science of viticulture and…

Polydatin as a therapeutic alternative for central nervous system disorders: A systematic review of animal studies

Polydatin, or piceid, is a natural stilbene found in grapes, peanuts, and wines. Polydatin presents pharmacological activities, including neuroprotective properties, exerting preventive and/or therapeutic effects in central nervous system (CNS)…

Food-Derived Bioactive Molecules from Mediterranean Diet: Nanotechnological Approaches and Waste Valorization as Strategies to Improve Human Wellness

The beneficial effects of the Mediterranean diet (MedDiet), the most widely followed healthy diet in the world, are principally due to the presence in the foods of secondary metabolites, mainly…

Piceatannol, a metabolite of resveratrol, attenuates atopic dermatitis by targeting Janus kinase 1

Background: Piceatannol is a resveratrol metabolite commonly found in red wine, grapes. Several studies have investigated the immune-modulating effects of piceatannol on processes related to allergic reactions. However, the relationship…

Green extraction of bioactive compounds from wine lees and their bio-responses on immune modulation using in vitro sheep model

The objective of this study was to apply microwave-assisted extraction using green solvents starting from 3 different wine (white, rosé, and red) lees and to test their bio-response on sheep…

White Wine-Induced Endothelium-Dependent Vasorelaxation in Sprague-Dawley Rats

The vasodilatory activity and polyphenolic content of commercially available white wine is low compared to red wines. This study assessed the vasodilator potential of white wines produced by four different…

Polyphenols and Ulcerative Colitis: An Exploratory Study of the Effects of Red Wine Consumption on Gut and Oral Microbiome in Active-Phase Patients

Scope: This paper explores the effects of moderate red wine consumption on the clinical status and symptomatology of patients with ulcerative colitis (UC), including the study of the oral and…

Alcohol Consumption and Cardiovascular Health

Background Studies evaluating alcohol consumption and cardiovascular diseases have shown inconsistent results. Methods We performed a systematic review of peer-reviewed publications from an extensive query of Ovid MEDLINE, Ovid Embase,…

Moderate Alcohol Use Is Associated with Reduced Cardiovascular Risk in Middle-Aged Men Independent of Health, Behavior, Psychosocial, and Earlier Life Factors

We examined whether the often-reported protective association of alcohol with cardiovascular disease (CVD) risk could arise from confounding. Our sample comprised 908 men (56–67 years), free of prevalent CVD. Participants…