Estudios científicos
Effect of drinking on adiponectin in healthy men and women: a randomized intervention study of water, ethanol, red wine, and beer with or without alcohol
Abstract:
OBJECTIVE: Moderate alcohol consumption is associated with reduced incidence of type 2 diabetes and cardiovascular mortality and increases adiponectin concentrations, but effects might differ according to sex and beverage consumed. RESEARCH DESIGN AND METHODS: A total of 72 healthy individuals (22-56 years) were enrolled in this randomized controlled crossover trial. After washout, two interventions for 3 weeks followed: ethanol (concentration 12.5%), beer (5.6%), or red wine (12.5%) equivalent to 30 g ethanol/day for men and 20 g/day for women or the same de-alcoholized beverages or water. Adiponectin was measured by sandwich enzyme-linked immunosorbent assay. RESULTS: Among women, adiponectin significantly increased after consuming red wine (29.8%, P < 0.05) and increased among men after ethanol solution (17.4%, P < 0.05) and consuming beer (16.1%, P < 0.05). De-alcoholized beverages had no substantial effect on adiponectin concentrations. CONCLUSIONS: Moderate amounts of ethanol-containing beverages increased adiponectin concentrations, but sex-specific effects might depend on type of beverage consumed.
Comentarios divulgativos:
Una consumición moderada de alcohol esta asociada con una reducción en la aparición de diabetes tipo 2, mortalidad debido a acontecimientos cardiovasculares y un incremento en las concentraciones de adiponectina. Sin embargo se han observado diferentes efectos dependiendo del sexo y del tipo de bebida consumida.
En este estudio un total de 72 individuos sanos de entre 22 y 56 años fueron estudiados proporcionándoles etanol, cerveza o vino tinto en concentraciones de 30g/día para los hombres y 20 g/día a las mujeres y se midieron las concentraciones de adiponectina. Un consumo moderado del etanol presente en las bebidas alcohólicas incrementa las concentraciones de adiponectina, sin embargo se observan diferentes efectos en los diferentes sexos dependiendo del tipo de bebida alcohólica.
